One of the most common symptoms of lipedema that is observed in all stages is swelling. This symptom is due to an increased amount of extracellular water causing the swelling. This extracellular water is lymphatic fluid that contains hundreds of inflammatory compounds that are responsible for fibrosis that drives the progression of lipedema. The increase of water will only increase with each further stage. One of the most frequently recommended forms of care for swelling and pain is wearing compression garments. This step in our multidisciplinary approach is typically recommended