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Diet & Supplement Recommendations and Rationale for Lipedema

Once you have been diagnosed with Lipedema your first steps should be to start these conservative non-invasive treatments, most importantly focused on your Lipedema nutrition

The Rare Adipose Disorder (RAD) Diet Is the Best Option When Living with Lipedema.

This Lipedema nutrition diet is a modification of the Mediterranean diet and emphasizes maintaining a low glycemic index by avoiding refined and processed starches, especially sugars and simple carbohydrates, such as white rice or potatoes. Experts also recommend adding in a gluten-free or low-gluten diet, avoiding wheat, rye, and barley, all of which cause gut inflammation and make lipedema symptoms flare up. Lipedema ketogenic diet could also work in some cases. 

Lipedema nutrition

Focus on eating fish, nuts, beans, and whole grains. Fats, such as Omega-3 and coconut oil are anti-inflammatory and fat-burning helpers. Focus on high fiber foods and the breakdown of the food pyramid below to help your body lose weight, reduce inflammation, and keep your gut healthy and happy!

Supplements, when paired with a healthy and consistent diet and exercise lifestyle, can offer patients positive improvements while dealing with lipedema symptoms. Patients should consult their physician before taking any supplements or changing their diets.


Selenium is a mineral that helps your metabolism and thyroid function properly, and has been shown to decrease swelling in tissue in two placebo-controlled trials for post-mastectomy and head and neck radiation. As we now know swelling can be a painful and unrelenting side effect of lipedema. Supplements may be difficult to obtain, but an accessible source of this mineral can be found in brazil nuts. Two brazil nuts a day will be sufficient for most people.

Vitamin D3:

Most patients with lipedema are vitamin D deficient. Vitamin D is essential for proper immune function and for bone, muscle, and nerve health. The US Recommended Daily Allowance (RDA) for Vitamin D for adults is 800 IU. For patients who are vitamin D3 deficient, 3 to 4 times the RDA is necessary to restore normal levels of Vitamin D3. You can read more about these levels here.


Diosmin is a bioflavonoid that is extracted from citrus fruits. Diosmin is the nutritional supplement that has the highest quality of evidence for its effectiveness on a broad range of vein and lymphatic problems. It can also be synthesized from a closely related citrus flavonoid, hesperidin. Diosmin has veno-tonic and lymph-tonic, anti-inflammatory, and antioxidant properties. This is the principal ingredient in the prescription supplement Vasculera.

Diosmin is useful in varicose veins, chronic venous insufficiency, hemorrhoids, venous ulcer healing, and lymphedema and lipedema. 

→Up Next: Exercise 

How to Tell Lipedema Apart from Regular Fat?

Lipedema fat is an abnormal accumulation of fat in specific areas – usually in the lower body, though fat accumulation is symmetrical, it’s painful and easily bruises. You can read more about the difference here


1 Micke, O., Bruns, F., Schäfer, U., Kisters, K., Hesselmann, S., and Willich, N. (2000) Selenium in the treatment of acute and chronic lymphedema. Trace Elements and Electrolytes 17, 206-209

2 Kasseroller, R. G., and Schrauzer, G. N. (2000) Treatment of secondary lymphedema of the arm with physical decongestive therapy and sodium selenite: a review. Am J Ther 7, 273-279

3 [] shows the effectiveness of Diosmin Diosmin significantly improved symptoms such as leg pain, heaviness, and cramps. Diosmin also improved leg edema or swelling and decreased leg circumference. Other studies have shown Diosmin improved venous ulcer healing, hemorrhoids, and lymphedema. [Citation]

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Meet Dr. Wright

Dr. Wright

Meet Dr. Thomas Wright, medical director of Laser Lipo and Vein Center. Dr. Wright is a board certified Phlebologist and cosmetic surgery specialist, with over 15 years of practicing experience. A graduate of the University of Missouri Columbia medical program, Dr. Wright was one of the first two hundred surgeons to become a diplomate in Phlebology.

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* Results May Vary From Person to Person